Fig. 2.

ScRNA-seq suggests a potential relationship between aging and migrasomes formation A. Mapping density plot of t-SNE showing the scoring result for the migrasome-associated gene TSPAN4. Dark blue color indicates maximum gene expression and grey color indicates low or no gene expression B. t-SNE diagram illustrated the cell clusters of fibroblasts C. Scatterplots showing the correlation between the six migrasome-associated genes (TSPAN4, TSPAN9, CPQ, EOGT, NDST1 and PIGK) and aging-related genes in the GenAge database respectively (see Methods for details). The trend lines represent the overall trend of all the scatter points in the corresponding plots, and the corresponding p-value and Spearman’s correlation coefficient are shown at the top of the plots