FIGURE 4.

GSK3B is downregulated in nasal mucus tissues and macrophages from AR patients. (A) GSK3B expression in nasal mucus tissues from healthy controls and AR patients was assessed by RT‐qPCR. (B,C) The mRNA and protein levels of GSK3B in macrophages derived from the nasal mucus of AR patients or healthy controls were assessed by RT‐qPCR and western blotting. (D–F) After OVA (5 mg/ml) treatment for 6, 12, 24, or 48 h, the mRNA and protein levels of GSK3B in macrophages from the nasal mucus of healthy controls were examined by RT‐qPCR and western blotting. (G) The correlation between miR‐214‐3p and GSK3B in nasal mucus tissues from AR patients (n = 28) was analyzed by Pearson correlation analysis. *p < 0.05, **p < 0.01