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. 2025 Mar 12;15:8460. doi: 10.1038/s41598-025-93190-3

Table 2.

Response surface analysis factor design for carboxymethylation.

Factor Level
Temperature (°C) 50 60 70
Dosage of Chloroacetic acid (g) 1.42 1.89 2.36
Concentration of Sodium hydroxide (mol/L) 1.5 2 2.5