Table 2. Comparative analyzes of the distributions of van der Waals contacts in representatives of the major fold types from A. aeolicus, E. coli, P. abyssi/horikoshii/furiosis, and T. maritima.

Source	Ec (124 ± 5.4)	Aa (133 ± 7.3)	Tm (127 ± 4.2)	Pr (139 ± 5.1)
Ec		1·10-4	4·10-2	<10-14
Aa			6·10-3	6·10-3
Tm				6·10-13

In parenthesis there are mean values approximated by normal distribution with three standard deviation intervals. P values show differences between mean values of the contact distribution for respective species. Aa, Ec, Pr, and Tm are A. aeolicus (22 folds), E. coli (34), P. abyssi/horikoshii/furiosus (37), and T. maritima (42), respectively.