TABLE 2.

The binding affinities of BSTs 1-5, RVX-208 and CJ-1383 to BRD4 and STAT3.

Compounds	BRD4 (K d, nM)	STAT3 (K d, nM)
BST-1	12.25 ± 1.16	16.43 ± 0.95
BST-2	3.62 ± 0.25	28.74 ± 3.71
BST-3	5.37 ± 0.49	8.42 ± 0.38
BST-4	1.46 ± 0.07	4.28 ± 0.59
BST-5	9.72 ± 0.84	13.73 ± 0.98
RVX-208	24.84 ± 2.31	no inhibition
CJ-1383	no inhibition	905 ± 12.67