Table 2.
Echocardiography measurements
| Pre-Breast Cancer | Post-Breast Cancer | |
|---|---|---|
| (n = 8) | (n = 8) | |
| LVIDd, cm | 0.67 ± 0.01 | 0.63 ± 0.03 |
| LVIDs, cm | 0.36 ± 0.01 | 0.33 ± 0.02 |
| LVPWd, cm | 0.18 ± 0.10 | 0.18 ± 0.02 |
| LVPWs, cm | 0.28 ± 0.01 | 0.31 ± 0.09 |
| FS, % | 46 ± 1 | 54 ± 4 |
| LVEDV, ml | 0.67 ± 0.05 | 0.60 ± 0.07 |
| LVESV, ml | 0.12 ± 0.01 | 0.10 ± 0.03 |
| SV, ml | 0.55 ± 0.04 | 0.52 ± 0.05 |
| EF, % | 82 ± 1 | 87 ± 3 |
| Heart rate (bpm) | 304 ± 6 | 314 ± 12 |
| Cardiac output (mL/min) | 167 ± 12 | 163 ± 17 |
| LV ΔP/ΔT (mmHg/s) | 8024 ± 191 ¥ | 8585 ± 717 |
| LVEDP (mmHg) | 2 ± 0 ¥ | 5 ± 1* |
Data are means ± SE. n, number of rats; LV, left ventricular; LVIDd, LV internal diameter in diastole; LVIDs, LV internal diameter in systole; LVPWd, LV posterior wall in diastole; LVPWs, LV posterior wall in systole; FS, fractional shortening; LVEDV, LV end diastolic volume; LVESV, LV end systolic volume; SV, stroke volume; EF, ejection fraction; bpm, beats per minute; LV ΔP/ΔT, LV change in pressure over change in time; LVEDP, LV end diastolic pressure;
P < 0.05 vs pre-breast cancer;
measured from subsample of healthy control rats (n = 5).