Table 3.
Cutoff points of ploidy and tumor markers for diagnosing SCLC
AUC | 95% CI | Sensitivity | Specificity | Cutoff value | |
---|---|---|---|---|---|
ProGRP | 0.928 | 0.877-0.978 | 0.824 | 1 | 151.05 |
NSE | 0.921 | 0.884-0.975 | 0.853 | 0.898 | 15.8 |
Max DI | 0.838 | 0.769-0.907 | 0.956 | 0.593 | 2.6395 |
Median DI | 0.862 | 0.795-0.930 | 0.75 | 0.949 | 2.557 |
Number of cells with DI greater than 5c | 0.962 | 0.933-0.991 | 0.956 | 0.831 | 5.5 |
5cER | 0.966 | 0.933-0.991 | 0.912 | 0.881 | 0.0142 |
Notes: Max DI represents the maximum DI. Median DI is the median DI of the first 20 cells greater than 5C. 5cER: 5c exceeding rate. We used 5cER to represent the percentage of cells with DI greater than 5c in this study.