Table 2. Differentiation of peripheral vertigo, central vertigo, and CBZ toxicity.
This table compares key features of peripheral vertigo, central vertigo, and CBZ toxicity. It highlights differences in symptoms, triggers, and physical findings, helping clinicians distinguish CBZ toxicity from other causes of dizziness.
CT: computed tomography; MRI: magnetic resonance imaging; CBZ: carbamazepine
Types of Vertigo | Peripheral Vertigo | Central Vertigo | Carbamazepine Toxicity (Drug-Induced Vertigo) |
Associated Symptoms | Tinnitus, hearing loss, ear fullness, nausea | Neurological symptoms (paralysis, numbness, speech impairment, diplopia), nausea, headache | Fatigue, drowsiness, nausea, confusion, ataxia, decreased consciousness, arrhythmia, syncope |
Onset | Acute, episodic | Sudden or gradual, persistent | Acute, persistent |
Triggers | Positional changes (head or body) | No specific triggers | Dose increase, addition of other medications |
Physical Findings | Horizontal nystagmus, direction-fixed nystagmus, mild balance disturbance, inner ear impairment | Vertical or direction-changing nystagmus, skew deviation, diplopia, dysarthria, dysphagia, dysphonia, dysmetria, dysdiadochokinesis | Vertical nystagmus, myoclonus, delayed reactions, impaired consciousness, seizures, diplopia, dysarthria, dysphagia, various other neurological findings |
Additional Tests | Hearing tests, caloric testing, positional nystagmus tests (vestibular function tests) | Brain MRI, CT, neurological examinations | Blood carbamazepine level testing; blood tests for liver/kidney function, and electrolyte |