T2D	type 2 diabetes
GLP-1	glucagon-like peptide 1
SGLT2	sodium-glucose cotransporter 2
DPP-4	dipeptidyl peptidase-4
NTS	nucleus of the solitary tract
GLP-1RA	GLP-1 receptor agonist
GLP-1R	GLP-1 receptor
cAMP	cyclic adenosine monophosphate
PKA	protein kinase A
cAMP-GEFII or Epac2	cAMP-regulated guanine nucleotide exchange factor
CREB	cAMP-responsive element binding
MACE	major adverse cardiovascular event
CVOTs	CardioVascular Outcome Trials
ICV	intracerebroventricular
BAT	brown adipose tissue
DPP-4i	dipeptidyl peptidase 4 inhibitor
sDPP-4	dipeptidyl peptidase 4 soluble
AGEs	advanced glycation end products
RAGE	advanced glycation end product receptor
ROS	reactive oxygen species
Ang	angiotensin
ACE	angiotensin I-converting enzyme
AT1R	Ang II type 1 receptor
HF	heart failure
STEMI	ST-segment elevation myocardial infarction
HCV	hepatitis C virus
ALT	alanine aminotransferase
AST	aspartate aminotransferase
ADA	adenosine deaminase
TGF	tubuloglomerular feedback
GFR	glomerular filtration rate
mProx24	proximal tubular epithelial cells
SGLT2is	SGLT2 inhibitors
HK2 cells	human kidney proximal tubular cell line
mTORC1	rapamycin complex 1
KB	ketone body
HFrEF	reduced ejection fraction
HFpEF	preserved ejection fraction
NOS	nitric oxide synthase
NHE	Na+/H+ exchanger CA
CA	cardiac arrest
ROSC	return of spontaneous circulation
MFN	mitofusin
DRP1	dynamin-related protein 1
AMP	adenosine monophosphate
AMPK	activated protein kinase
OPA1	optic atrophy 1
Fis-1	fission 1
GIP	glucose-dependent insulinotropic polypeptide