Definitions
APC	Antigen-presenting cells
CAF	Cancer-associated fibroblasts (CAFs)
CD	Cluster of Differentiation
CEACAM	Carcinoembryonic antigen-related cell adhesion molecules
CRC	Colorectal cancer
CTLA-4	Cytotoxic T-lymphocyte associated protein-4
CTX	Chemotherapy
dMMR	Deficient mismatch repair
DCA	Deoxycholic acid
DC	Dendritic cells
EBV	Epstein Barr virus
ECM	Extracellular matrix
FMT	Fecal microbiota transplantation
5-FU	5-fluorouracil
GC	Gastric cancer
HBV	Hepatitis B virus
HCV	Hepatitis C virus
HIF	Hypoxia-inducible factor
HPV	Human papillomavirus
HTLV-1	Human T-cell lymphotropic virus type 1
ICIs	Immune checkpoint inhibitors
irAEs	Immune-related adverse events
ITIM	Immunoreceptor tyrosine-based inhibitory motifs
LAG-3	Lymphocyte activation gene 3
LPS	Lipopolysaccharide
MDSCs	Myeloid-derived suppressor cells
MSI-H	Microsatellite instability-high
NK	Natural killer
PDAC	Pancreatic ductal adenocarcinoma
PD-1	Programmed cell death protein-1
PD-L1	Programmed cell death protein-1 ligand
PRR	Pattern recognition receptors
ROS	Reactive oxygen species
RT	Radiation therapy
SCFA	Short-chain fatty acids
TAMs	Tumor-associated macrophages
TIM-3	T-cell immunoglobulin and mucin domain 3
TIME	Tumor-immune microenvironment
TIGIT	T-cell immunoglobulin and ITIM
TIL	Tumor-infiltrating lymphocytes
TME	Tumor microenvironment
Tregs	Regulatory T cells