| ACSL3 | Acyl-coenzyme A (CoA) synthetase long-chain family member 3; |
| AKT | Protein kinase B; |
| AMPK | 5′ AMP-activated protein kinase; |
| 6-AN | 6-anicotinamide; |
| Anlo | Anlotinib; |
| APC | Adenomatous polyposis coli; |
| ASK1 | Apoptosis signal-regulating kinase 1; |
| ATPP-DTPA | 5-(4-amino-phenyl)-10,15,20-triphenylporphyrin-diethylene-triaminopentaacetic acid; |
| ATF4 | Activating transcription factor 4; |
| BER | Base excision repair; |
| BMP | Bone morphogenetic protein; |
| BRAF | B-Raf proto-oncogene; |
| CAFs | Cancer-associated fibroblasts; |
| CAT | Catalase; |
| CDDP | Cisplatin; |
| CDK | Cyclin-dependent kinase; |
| CIN | Chromosomal instability; |
| CIOSS | CRC-integrated OS score; |
| CM-H2DCFDA | 5-(and 6)-chloromethyl-2′,7′-dichlorohydrofluorescein diacetate; |
| COX-2 | Cyclooxygenase-2; |
| CPT-11 | Irinotecan; |
| CRC | Colorectal cancer; |
| CTLA-4 | Cytotoxic T lymphocyte-associated protein 4; |
| CtBP1 | C-terminal binding protein-1; |
| CXCL2 | C-X-C motif chemokine ligand 2; |
| Cyt-c | Cytochrome-c; |
| DCF | 2′,7′-dichlorofluorescein; |
| DHA | Dihydroartemisinin; |
| DHE | Dihydroethidium; |
| d-ROMs | Reactive oxygen metabolite derivatives; |
| Dvl | Dishevelled protein 1; |
| DTNB | 5,5′-dithio-bis(2-nitrobenzoic acid); |
| EGFR | Epidermal growth factor receptor; |
| ELISA | Enzyme-linked immunosorbent assay; |
| EMT | Epithelial-to-mesenchymal transition; |
| ER | Endoplasmic reticulum; |
| ERK | Extracellular signal-regulated kinase; |
| FGFR | Fibroblast growth factor receptor; |
| FLIM | Fluorescence lifetime imaging microscopy; |
| 5-FU | 5-fluorouracil; |
| G6PD | Glucose-6-phosphatedehydrogenase; |
| GGT2 | Gamma-glutamyltransferase 2; |
| GOT1 | Glutamic-oxaloacetic transaminase 1; |
| GPXs | Glutathione peroxidases |
| GSH | Glutathione; |
| GSS | Glutathione synthase; |
| GSSG | Oxidized glutathione |
| GSTs | Glutathione S-transferases; |
| Gyp | Gypenosides; |
| H2DCF | 2′,7′-dichlorodihydrofluorescein; |
| H2DCFDA | 2′,7′-dichlorodihydrofluorescein diacetate; |
| H2O2 | Hydrogen peroxide; |
| HER | Human epidermal growth factor receptor; |
| HIF-1α | Hypoxia-inducible factor 1α; |
| HPLC | High-pressure liquid chromatography; |
| HY-PDT | Photodynamic therapy mediated by hypericin; |
| IBD | Inflammatory bowel diseases; |
| ICAM-1 | Intercellular adhesion molecule 1; |
| IFN | Interferon; |
| IFN-α | Interferon-alpha; |
| IKK | Inhibitor κB kinase; |
| ISC | Intestinal stem cell; |
| JAK | Janus kinase; |
| JNK | c-Jun N-terminal kinase; |
| Keap1 | Kelch-like ECH-associated protein 1; |
| KRAS | KRAS proto-oncogene, GTPase; |
| LncRNAs | Long noncoding RNAs; |
| L-OHP | Oxaliplatin; |
| mAbs | Monoclonal antibodies; |
| MAPK | Mitogen-activated protein kinase; |
| MAP3K | Mitogen-activated protein kinase kinase kinase; |
| MDA | Malondialdehyde; |
| MDR | Multidrug resistance; |
| MEK | Mitogen-activated protein kinase kinase-MAPKK; |
| MET | Metformin; |
| MLK3, MAP3K11 | Mixed lineage kinase 3; |
| MMR | Mismatch repair; |
| MPO | Myeloperoxidase; |
| MSI | Microsatellite instability; |
| MSI-H | Microsatellite instability-high; |
| mTOR | Mammalian target of rapamycin; |
| MUTYH | MutY homolog Escherichia coli, homolog of MYH, hMYH; |
| MVs | Membrane vesicles; |
| NaB | Sodium butyrate; |
| NAC | N-acety1 cysteine; |
| NADPH | Nicotinamide adenine dinucleotide phosphate; |
| NPs | Nanoparticles; |
| NER | Nucleotide excision repair; |
| NF-κB | Nuclear factor kappa B; |
| NIK | NF-κB inducing kinase; |
| NOTCH | Notch receptor; |
| NOX | NADPH oxidase; |
| NRAS | NRAS proto-oncogene, GTPase; |
| NRF2 | Nuclear factor-erythroid 2 p45-related factor 2; |
| NRX | Nucleoredoxin; |
| NSAIDs | Nonsteroidal anti-inflammatory drug; |
| O2•− | Superoxide anion; |
| OGG1 | 8-oxoguanine DNA glycosylase 1; |
| •OH | Hydroxyl radical; |
| 8-OHdG | 8-hydroxy-2′-deoxyguanosine; |
| 8-oxoG | 8-oxoguanine; |
| 8-oxodG | 8-oxo-7, 8-dihydro-2′-deoxyguanosine; |
| oxLDL | Oxidized low-density lipoprotein; |
| OS | Oxidative stress |
| P3C-Asp | Dextran–aspirin nanomedicine; |
| PD-1 | Programmed cell death 1; |
| PDGF-R | Platelet-derived growth factor receptors; |
| PDL1 | Programmed death ligand 1; |
| PDT | Photodynamic therapy; |
| PFL | Positive feedback loop; |
| P-gp | P-glycoprotein; |
| PI3K | Phosphatidyl inositol 3-OH kinase; |
| PKB | Protein kinase B; |
| PL | Piperlongumine; |
| PMN | Polymorphonuclear; |
| PPP | Pentose phosphate pathway; |
| PRX | Peroxiredoxin; |
| PTEN | Phosphatase and tensin homolog; |
| PTKs | Protein tyrosine kinases; |
| PTP | Protein tyrosine phosphatase; |
| PUFAs | Polyunsaturated fatty acids; |
| PL | Piperlongumine; |
| qPCR | Quantitative real-time polymerase chain reaction; |
| RAC1 | Rac family small GTPase 1; |
| ROS | Reactive oxygen species; |
| RTKs | Receptor tyrosine kinases; |
| SA | Salicylic acid; |
| SalB | Salvianolic acid B; |
| SCD1 | Stearoyl-CoA desaturase-1; |
| SLC7A11 | Solute carrier family 7 member 11; |
| SMAD4 | SMAD family member 4/mothers against decapentaplegic homolog 4; |
| SOD | Superoxide dismutase; |
| STAT | Signal transducer of activators of transcription; |
| TALDO1 | Transaldolase 1; |
| TAMs | Tumor-associated macrophages; |
| TANs | Tumor-associated neutrophils; |
| TBA | Modified 2-thiobarbituric acid; |
| TBARS | Thiobarbituric acid reactive; |
| TCA | Tricarboxylic acid cycle; |
| TCF-4 | T-cell factor-4; |
| TCRs | T-cell receptors; |
| TIGAR | TP53-induced glycolysis regulatory phosphatase; |
| TGF-β | Transforming growth factor-β; |
| TKI | Tyrosine kinase inhibitor; |
| TME | Tissue microenvironment; |
| TNFR | Tumor necrosis factor receptor; |
| TRAF3 | Tumor necrosis factor receptor-associated factor 3; |
| Trx/TrxR | Thioredoxin/thioredoxin reductase; |
| VCAM1 | Vascular cell adhesion molecule 1; |
| VEGF | Vascular endothelial growth factor; |
| VEGFR | Vascular endothelial growth factor receptor; |
| Wnt | Wingless/It; |
| Wnt-PCP | Wnt-planar cell polarity; |
| xCT | xc− transporter; |
| X-PDT | X-ray-induced photodynamic therapy. |