Table 2.
Therapy Group | n | WBC × 103/μL | RBC × 106/μL | Platelets × 103/μL | Micronuclei (%RBC) |
Early1 | |||||
Control | 4 | 2.91 ± 0.83 | 9.08 ± 0.07 | 584 ± 76 | 1.3 ± 0.04 |
IR | 4 | 0.11 ± 0.01 | 7.50 ± 0.16 | 389 ± 17 | 1.2 ± 0.03 |
TEMF | 5 | 2.89 ± 0.60 | 9.05 ± 0.12 | 505 ± 61 | 1.3 ± 0.04 |
TEMF/IR | 4 | 0.23 ± 0.06 | 7.68 ± 0.13 | 443 ± 34 | 1.2 ± 0.03 |
Late2 | |||||
Control | 8 | 1.85 ± 0.37 | 8.30 ± 0.14 | 551 ± 83 | 1.6 ± 0.06 |
IR | 13 | 1.48 ± 0.332 | 7.06 ± 0.16 | 973 ± 98 | 0.7 ± 0.01 |
TEMF | 11 | 1.15 ± 0.29 | 8.85 ± 0.22 | 613 ± 62 | 0.7 ± 0.01 |
TEMF/IR | 10 | 1.07 ± 0.13 | 6.58 ± 0.11 | 1007 ± 141 | 0.6 ± 0.01 |
1Mice sacrificed one day after last irradiation treatment.
2Mice sacrificed 22 days after last irradiation treatment.
Results of Statistical Analyses:
1. At the end of irradiation therapy plus one day, gamma irradiation caused significant decreases in WBC, RBC, and platelet counts. No other significant differences at p < 0.01.
2. At the end of irradiation therapy plus 22 days, gamma irradiation caused significant decreases in WBC and RBC counts and a significant increase in platelet counts. No other significant differences at p < 0.01.