TABLE 2.
Multiply used rearrangement breakpoints are observed more frequently than expected
| Breakpoint usagea | No. of source breakpointsb (avg identity length)
|
No. of target breakpointsb (avg identity length)
|
||||
|---|---|---|---|---|---|---|
| Last IDc | First IDc | Randomd | Last IDc | First IDc | Randomd | |
| 1 | 286 (3.3) | 299 (3.3) | 348 | 281 (3.7) | 282 (3.7) | 334 |
| 2 | 31 (3.7) | 25 (3.4) | 10 | 24 (4.5) | 23 (4.7) | 0 |
| 3 | 2 (2.2) | 3 (6.0) | 0 | 3 (4.9) | 2 (8.5) | 0 |
| 4 | 1 (8.25) | 0 | 0 | 0 | 0 | 0 |
a
Number of times that any single nucleotide was at a rearrangement.
b
Number of nucleotide positions that are rearrangements.
c
Distributions calculated using the first and last identifiable definitions for breakpoints (see Fig. 2A).
d
Number of identical breakpoints that would be predicted by a Poisson distribution of 358 events in 12 kb (for the chromosome V source) or 334 events in 12 Mb (for the unique genome targets).