FIG. 3.

In vitro activity of mutant Psc proteins of engineered deletion constructs. (A) Inhibition of chromatin remodeling by mutant Psc (concentrations as indicated in panel B). All lanes are from the same experiment and are arranged so that identical concentrations of Psc are vertically aligned. The titration of PSC^1-572 was extended to concentrations higher than that for the other proteins because of the lower activity of PSC^1-572. (B) Summary of inhibition of chromatin remodeling by mutant Psc. Standard error is shown. (C) Inhibition of transcription by mutant Psc (6, 12, 24, 48 nM).