FIG. 5.

The UNC-5-SRC-1 fusion protein is able to rescue the motor neuron defect caused by the unc-5 mutation. (A and B) Commissural axon structure for unc-5(e53) (A) and the unc-5(e53) line with the fusion construct (B) are shown. The axon structure is visualized with the plx-2::GFP construct. The plx-2 promoter expresses GFP protein on B-type motor neurons. White arrows denote commissural axons for motor neurons. The anterior side is to the left, and the dorsal side is on top. The dotted line indicates the dorsal edge of worms. (C) Percentages of proper commissural axon crossing for the respective genotypes were shown along with standard deviations. Total numbers of worms observed are also shown. wt, wild type.