Table 2.
Correlations between clinical characteristics and GABA+/Cr and Glx/Cr levels in ACC.
| GABA+/Cr in ACC | Glx/Cr in ACC | |||
|---|---|---|---|---|
| r | p | r | p | |
| Duration (months) | 0.364 | 0.025* | 0.122 | 0.465 |
| PTA (dB HL) | −0.241 | 0.146 | −0.300 | 0.068 |
| PM (Hz) | 0.039 | 0.818 | 0.421 | 0.008* |
| LM (dB HL) | −0.035 | 0.834 | 0.171 | 0.306 |
| VAS | 0.116 | 0.489 | 0.233 | 0.160 |
| TFI | 0.079 | 0.637 | 0.232 | 0.161 |
| TFI-I | 0.184 | 0.268 | 0.312 | 0.056 |
| TFI-SC | −0.062 | 0.712 | 0.305 | 0.062 |
| TFI-C | 0.055 | 0.743 | 0.210 | 0.207 |
| TFI-SL | 0.028 | 0.865 | 0.050 | 0.764 |
| TFI-A | −0.080 | 0.634 | −0.031 | 0.851 |
| TFI-R | 0.242 | 0.143 | 0.057 | 0.732 |
| TFI-Q | 0.097 | 0.562 | 0.106 | 0.527 |
| TFI-E | −0.048 | 0.776 | 0.370 | 0.022* |
ACC, anterior cingulate cortex; PTA, pure-tone average; PM, pitch match; LM, loudness match; L, left ear; R, right ear; B, bilateral; VAS, visual analog scale; TFI, Tinnitus Functional Index; TFI-I, Tinnitus Functional Index–Intrusive; TFI-SC, Tinnitus Functional Index–Sense of Control; TFI-C, Tinnitus Functional Index–Cognitive; TFI-SL, Tinnitus Functional Index–Sleep; TFI-A, Tinnitus Functional Index–Auditory; TFI-R, Tinnitus Functional Index–Relaxation; TFI-Q, Tinnitus Functional Index–Quality of Life; TFI-E, Tinnitus Functional Index–Emotional. *Uncorrected p-values < 0.05. Statistical results are presented as Pearson’s correlation coefficient (r) and significance level (p).