Table 1.

Baseline characteristics and comparison of treatment groups.

	CLAD (n = 28)	ALEM (n = 19)	p-value
Age (years, mean)	35.70	33.84	0.512
Duration of the disease (years, mean)	8.56	7.33	0.423
Number of previous DMTs (mean)	2.18	2.78	0.110
EDSS score	2.75	3.97	0.004
ARR	1.39	2.26	0.008
Number of new T2 lesions	3.75	6.26	0.03
Number of new Gd+ lesions	1.42	2.89	0.47

Statistically significant values are bolded. DMTs, disease modifying therapies; EDSS, Expanded Disability Status Scale; ARR, annualised relapse rate; T2, lesions–lesions on T2-weighted magnetic resonance imaging; Gd+, contrast-enhancing lesions.