Table 4.
Analysis of the determinants of the paired mean differences between the healthy and affected brain hemispheric sides in the GBM subgroup
| Outcome: IFOF mean length (mm) in GBM | Outcome: IFOF volume (cm3) in GBM | |||||
|---|---|---|---|---|---|---|
| Characteristic | Adj. β | 95% CI | p-value | Adj. β | 95% CI | p-value |
| Group | ||||||
| Affected | — | — | — | — | ||
| Healthy | 7.4 | 5.5, 9.3 | < 0.001 | 12 | 9.5, 14 | < 0.001 |
| Sex | ||||||
| Female | — | — | — | — | ||
| Male | 2.9 | −5.0, 11 | 0.469 | 3.2 | −0.15, 6.5 | 0.061 |
| Age (y) | 0.16 | −0.23, 0.56 | 0.415 | −0.13 | −0.30, 0.04 | 0.132 |
| Side | ||||||
| Left | — | — | — | — | ||
| Right | −1.4 | −10, 7.3 | 0.751 | −0.05 | −3.7, 3.6 | 0.977 |
| Volume – EN cm3 | −0.51 | −0.74, −0.27 | < 0.001 | 0.19 | 0.09, 0.29 | < 0.001 |
|
Volume—FLAIR hyperintensity beyond EN cm3 |
−0.02 | −0.15, 0.11 | 0.752 | −0.09 | −0.14, −0.03 | 0.002 |
IFOF, inferior fronto-occipital fasciculus, Adj. β adjusted beta value, CI confidence interval, GBM glioblastoma multiforme, EN enhancing nodule