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. 2025 Feb 27;16:1529327. doi: 10.3389/fphar.2025.1529327

TABLE 2.

The CAMARADES quality items.

Study ① ② ③ ④ ⑤ ⑥ ⑦ ⑧ ⑨ ⑩ Quality score
He et al. (2020) √ √ √ N N N √ ? N √ 5
Liao (2020) √ √ √ N N N √ √ √ √ 7
Liao et al. (2019) √ √ √ N N N √ √ N √ 6
Mei et al. (2010) √ √ √ N N N √ √ N √ 6
Wan (2022) √ √ √ N N N √ √ √ √ 7
Sheraz (2019) √ √ √ N N N √ √ √ √ 7
Fang et al. (2021) √ √ √ N N N √ ? N √ 5
Mei et al. (2009) √ √ √ N N N √ √ N √ 6
Ma et al. (2022) √ √ √ N N N √ √ √ √ 7
Xiang et al. (2024) √ √ √ N N N √ √ √ √ 7
He et al. (2020) √ √ √ N N N √ √ √ √ 7
Ding et al. (2020) √ √ √ N N N √ √ √ √ 7
Peng et al. (2022) √ √ √ N N N √ √ √ √ 7
Liu et al. (2016) √ √ √ N N N √ √ √ √ 7

(1) peer reviewed publication; (2) presence of randomization of subjects into treatment groups; (3) assessment of dose-response relationship; (4) blinded assessment of behavioural outcome; (5) monitoring of physiological parameters such as body temperature; (6) calculation of necessary sample size to achieve sufficient power; (7) statement of compliance with animal welfare regulations; (8) avoidance of anaesthetic agents with marked intrinsic neuroprotective properties (e.g., ketamine); (9) statement of potential conflict of interests; (10) use of a suitable animal model.

Abbreviations: √, fulfilling the criterion; N, not fulfilling the criterion; ?, not enough information to determine whether or not the criterion is fulfilled.