Skip to main content
. 2025 Feb 28;10(9):9703–9717. doi: 10.1021/acsomega.4c11076

Figure 4.

Figure 4

Efficacy of compounds 4 and 5 in an in vivo murine model of MRSA skin infection: Twenty-eight BALB/C mice were divided into four groups (n = 7). A: Photographic image showing the efficacy of different treatment groups on MRSA skin infection on the posterior backs of mice at the end of the experiment. B: Efficacy of different treatment groups on bacterial load in the murine model of MRSA skin infection. Each data point represents a mouse. Results are expressed as mean ± standard error. **** indicates a significant difference at p < 0.0001 (one-way ANOVA, Tukey’s posthoc test).2.2.4. In-vitro assay against S. aureus DNA gyrase.