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. 2025 Jan 21;12(10):2407574. doi: 10.1002/advs.202407574

Figure 2.

Figure 2

Expression levels of MDV‐related genes in single‐cell sequencing data. A) UMAP dimensionality reduction embedding of data from Healthy individuals, those with Diabetes, and those with DFU. B) Human single‐cell RNA sequencing dot plot demonstrating gene expression within various clusters; these clusters were identified using UMAP cluster analysis, as shown in (A). C) Human single‐cell RNA sequencing dot plot demonstrating gene expression within Healthy, Diabetes, and DFU samples. D) qRT‐PCR assay results (RAB9A, PRKN, VPS35, STX17, TOLLIP, DNM1L, SNX9, and OPA1). Statistical analysis was performed using one‐way ANOVA (Healthy, n = 3; Diabetes, n = 5; DFU, n = 5). Data are presented as the mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.