| – Allergy documented but denied by patient |
| – Isolated gastrointestinal reaction: diarrhea, nausea, vomiting (to be distinguished from spontaneous occurrence in anaphylactic reactions together with other anaphylactic symptoms) |
| – Isolated non-specific reaction: dizziness, headache, fatigue, palpitation, rhinoconjunctivitis (often associated with fear of drug hypersensitivity) |
| – Delayed urticaria: occurrence > 1 day after discontinuation or persisting for days after discontinuation |
| – Mild exanthema: occurrence > 1 week after discontinuation |
| – Positive family history without personal allergy history |
| – Isolated generalized or localized pruritus without further skin changes and without warning signs of anaphylaxis (burning/tingling of tongue/palate, palm/sole of foot or genitals, feeling of heat, coughing, difficulty swallowing, reddening of large areas of skin) |
| – Anamnestic tolerance of the suspected β-lactam antibiotic administered (accidentally) |
|
Procedure: Direct administration of β-lactam antibiotic without allergologic diagnostics. Direct delabeling (documentation in patient file/written information for further GP care/education of patient), collection of allergy passport/card if necessary. |
