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. 2025 Feb 26;63(3):171–180. doi: 10.1038/s41393-025-01065-1

Table 1.

Inclusion and exclusion criteria.

Characteristic Inclusion Exclusion
Population

‐ Patient with cervical myelopathy

‐ Patients 18 years old or more

‐ Patients with spondylosis but do not exhibit myelopathy

‐ Thoracic or lumbar myelopathy

‐ Patients with traumatic cervical spinal cord injury

‐ Patients with tumour or infection

Clinical sign

‐ Tromner’s’ sign

‐ Babinski

‐ Hoffmann

‐ Clonus

‐ Inverted supinator

‐ Hyperreflexia (biceps, triceps, patella, brachioradialis, Achilles)

‐ Tandem gait

‐ Other clinical signs

‐ Studies using imaging modalities to diagnose DCM

‐ Patient (e.g., neck disability index, Visual Analog Scale, SF-36) or clinician (e.g., Nurick grade, mJOA score) reported outcome measures

Symptom

‐ Neck pain

‐ Autonomic dysfunction

‐ Hand numbness

‐ Hand paraesthesia

‐ Upper extremity weakness

‐ Loss of dexterity

‐ Other symptoms

Outcomes ‐ Sensitivity and specificity of clinical signs and symptoms ‐ Studies reporting only frequencies for clinical signs and symptoms
Study Design ‐ Case – controlled studies with suitable control groups (e.g., individuals with cervical radiculopathy or axial neck pain who do not exhibit myelopathic symptoms)

‐ Review articles

‐ Studies with no control group

‐ Animal studies

‐ Case series, reports