Table 2.
Baseline characteristics for all participants stratified by all-cause mortality (ACM)
| ACM | No-ACM | P-value | |
|---|---|---|---|
| N (%) | 651 (6.2) | 9829 (93.8) | |
| Age [years] | 71 (63, 79) | 64 (56, 73) | <0.001 |
| Male | 398 (61.1) | 5347 (54.4) | <0.001 |
| BMI [kg/m2] | 27 (24, 32) | 29 (25, 33) | <0.001 |
| Hypertension | 417 (64.1) | 5758 (58.6) | 0.007 |
| Diabetes mellitus | 230 (35.3) | 2454 (25.0) | <0.001 |
| Dyslipidemia | 329 (50.5) | 4756 (48.4) | 0.307 |
| Smoking | 125 (19.2) | 1862 (18.9) | 0.913 |
| Family history of CAD | 135 (20.7) | 2636 (26.8) | <0.001 |
| Prior CAD | |||
| Prior Myocardial Infarction | 69 (10.6) | 681 (6.9) | <0.001 |
| Past PCI | 126 (19.4) | 1382 (14.1) | <0.001 |
| Past CABG | 84 (12.9) | 552 (5.6) | <0.001 |
| CT Quantitative Image Analysis Parameters | |||
| DL CAC score | 353 (25, 1718) | 48 (0, 652) | <0.001 |
| DL EAT volume [mL] | 143 (93,198) | 130 (90, 182) | 0.003 |
| DL EAT density [HU] | −65 (−69, −60) | −65 (−70, −61) | <0.001 |
| MPI Acquisition Parameters | |||
| Stress Test Type | <0.001 | ||
| Exercise | 156 (24.0) | 4576 (46.6) | |
| Pharmacological | 495 (76.0) | 5253 (53.4) | |
| Peak Stress Heart Rate | 93 (79, 116) | 114 (90, 146) | <0.001 |
| Peak stress systolic blood pressure | 130 (114, 150) | 149 (128, 170) | <0.001 |
| Peak stress diastolic blood pressure | 70 (62, 80) | 80 (70, 87) | <0.001 |
| ECG response to stress | <0.001 | ||
| Negative | 518 (79.6) | 7492 (76.2) | |
| Positive | 52 (8.0) | 1115 (11.3) | |
| Equivocal | 11 (1.7) | 444 (4.5) | |
| Nondiagnostic | 69 (10.6) | 755 (7.9) | |
| Borderline | 1 (0.2) | 9 ( < 0.1) | |
| MPI quantitative image analysis parameters | |||
| Stress ejection fraction | 58 (45, 68) | 64 (56, 72) | <0.001 |
| Stress end diastolic volume | 93 (70, 130) | 83 (64, 110) | <0.001 |
| Stress shape index end diastolic | 0.60 (0.56, 0.65) | 0.58 (0.53, 0.62) | <0.001 |
| Stress total perfusion deficit | 4.4 (1.7, 9.9) | 2.5 (0.8, 5.8) | <0.001 |
Values are presented as N (%) or median (IQ1, IQ3).
BMI body mass index, CABG coronary artery bypass graft, CAC coronary artery calcium, CAD coronary artery disease, CT computed tomography, DL deep learning, EAT epicardial adipose tissue; ECG electrocardiogram, HU Hounsfield units, MPI myocardial perfusion imaging, PCI percutaneous coronary intervention.