Table 2.
Classification of patients with acute pulmonary embolism according to the mortality risk and the ability of central thrombus location on CT angiography to correctly classify intermediate-high risk pulmonary embolism
|
Peripheral PE N = 238 |
Central PE N = 117 |
P value | |
|---|---|---|---|
| Classification of PE risk, N (%) | |||
| Low risk | 91/238 (38.2) | 11/117 (9.4) | |
| Intermediate low risk | 89/238 (37.4) | 35/117 (27.4) | < 0.0001 |
| Intermediate high risk | 23/238 (9.7) | 47/117 (40.2) | |
| High risk | 35/238 (14.7) | 27/117 (23.1) | |
| Unable to classify* | 67/305 (22.0) | 16 /133 (12.0) | 0.02 |
| Diagnostic performance of central thrombus location to correctly classify PE as intermediate-high risk (analysis was performed in patients without hypotension) | |||
| Value | 95% confidence interval | ||
| Sensitivity | 67.1% | 54.9% to 77.9% | |
| Specificity | 79.7% | 73.8% to 84.7% | |
| Positive Likelihood Ratio | 3.30 | 2.43 to 4.48 | |
| Negative Likelihood Ratio | 0.41 | 0.29 to 0.58 | |
| Positive Predictive Value | 50.5% | 43.0% to 58.1% | |
| Negative Predictive Value | 88.7% | 84.8% to 91.7% | |
| Accuracy | 76.7% | 71.5% to 81.4% | |
PE Pulmonary embolism
*: lack of data needed for classification (brain natriuretic peptide, troponin I, or echocardiography)