Table 3.
Management of patients with acute PE
| Variables |
All patients N = 438 |
Peripheral PE N = 305 |
Central PE N = 133 |
P value |
|---|---|---|---|---|
| Troponin I measured, N (%) | 374 (85.4) | 257 (84.3) | 117 (88.0) | 0.31 |
| BNP measured, N (%) | 326 (74.4) | 221 (72.5) | 105 (78.9) | 0.15 |
| Echocardiography performed, N (%) | 167 (38.1) | 96 (31.5) | 71 (53.4) | < 0.0001 |
| Lower limb Doppler ultrasound, N (%) | 131 (29.9) | 82 (26.9) | 49 (36.8) | 0.04 |
| DVT present, N (%) | 51/131 (38.9) | 26/82 (31.7) | 25/49 (51.0) | 0.03 |
| Systemic anticoagulation, N (%) | 434 (99.1) | 301 (98.7) | 133 (100.0) | 0.19 |
| Systemic thrombolysis, N (%) | 19 (4.3) | 6 (2.0) | 13 (9.8) | < 0.0001 |
| 50 mg tPA | 9/19 (47.4) | 2/6 (33.3) | 7/13 (53.8) | 0.63 |
| 100 mg tPA | 10/19 (52.6) | 4/6 (66.7) | 6/ 13 (46.2) | 0.63 |
| Any endovascular treatment, N (%) | 17 (3.9) | 2 (0.7) | 15 (11.3) | < 0.0001 |
| Catheter-directed thrombolysis | 13 (3.0) | 2 (0.7) | 11 (8.3) | < 0.0001 |
| Mechanical thrombectomy | 12 (2.7) | 1 (0.3) | 11 (8.3) | < 0.0001 |
| Surgical thrombectomy, N (%) | 1 (0.2) | 0 (0) | 1 (0.8) | 0.30 |
| Inferior vena cava filter, N (%) | 29 (6.6) | 15 (4.9) | 14 (10.5) | 0.03 |
| Respiratory support on the day of diagnosis, N (%) | ||||
| Room air or simple oxygen therapy | 423 (96.6) | 296 (97.0) | 127 (95.5) | |
| Non-invasive ventilation | 8 (1.8) | 6 (2.0) | 2 (1.5) | 0.29 |
| Invasive mechanical ventilation | 7 (1.6) | 3 (1.0) | 4 (3.0) | |
| Fraction of inspired oxygen (%), median (Q1, Q3) | 21 (21, 28) | 21 (21, 28) | 24 (21, 28) | 0.003 |
| Admission to the ICU, N (%) | 110 (25.1) | 58 (19.0) | 52 (39.1) | < 0.0001 |
| Vasopressor use during hospital stay, N (%) | 32 (7.3) | 19 (6.2) | 13 (9.8) | 0.19 |
| Invasive mechanical ventilation during hospital stay, N (%) | 38 (8.7) | 23 (7.5) | 15 (11.3) | 0.20 |
BNP B-type natriuretic peptide, DVT Deep-vein thrombosis, ICU Intensive care unit, PE Pulmonary embolism, Q1 First quartile, Q3 Third quartile, tPA tissue plasminogen activator