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. 2025 Mar 12;23:22. doi: 10.1186/s12959-025-00708-w

Table 5.

Results of the multivariable logistic regression analysis for the predictors of hospital mortality and six-month mortality

Hospital mortality Six-month mortality
Model 1* Model 2** Model 1* Model 2**
Odds ratio (95% CI) P-value Odds ratio (95% CI) P-value Odds ratio (95% CI) P-value Odds ratio (95% CI) P-value
Age per year increment 1.005 (0.976, 1.035) 0.73 1.005 (0.977, 1.034) 0.73 1.021 (1.000, 1.042) 0.046 1.020 (1.000, 1.041) 0.051
Female vs. male sex 1.584 (0.528, 4.756) 0.41 1.611 (0.538, 4.827) 0.39 0.900 (0.446, 1.816) 0.77 0.931 (0.460, 1.881) 0.84
Obesity (BMI ≥ 30 kg/m2) vs. no obesity 1.648 (0.643, 4.225) 0.30 1.586 (0.624, 4.031) 0.33 0.476 (0.235, 0.964) 0.04 0.443 (0.219, 0.895) 0.02
Diabetes vs. no diabetes 1.584 (0.528, 4.756) 0.45 1.363 (0.455, 4.080) 0.58 1.867 (0.844, 4.131) 0.12 1.828 (0.831, 4.020) 0.13
Hypertension vs. no hypertension 0.806 (0.246, 2.638) 0.72 0.919 (0.288, 2.929) 0.89 1.114 (0.469, 2.647) 0.81 1.151 (0.488, 2.712) 0.75
Hyperlipidemia vs. no hyperlipidemia 0.811 (0.283, 2.325) 0.70 0.797 (0.279, 2.272) 0.67 0.786 (0.386, 1.601) 0.51 0.765 (0.377, 1.552) 0.46
History of myocardial infarction vs. no history 0.609 (0.115, 3.221) 0.56 0.646 (0.124, 3.355) 0.60 0.383 (0.112, 1.312) 0.13 0.418 (0.122, 1.435) 0.17
CKD vs. no CKD 1.013 (0.252, 4.068) 0.99 1.145 (0.293, 4.478) 0.85 1.563 (0.595, 4.102) 0.37 1.893 (0.720, 4.981) 0.20
Heart failure vs. no heart failure 0.609 (0.115, 3.221) 0.49 1.722 (0.402, 7.380) 0.46 1.474 (0.530, 4.099) 0.46 1.614 (0.579, 4.499) 0.36
COPD vs. no COPD 0.609 (0.115, 3.221) 0.89 0.964 (0.071, 13.130) 0.98 0.979 (0.114, 8.420) 0.99 0.843 (0.100, 7.096) 0.88
Malignancy vs. no malignancy 1.336 (0.362, 4.930) 0.66 1.340 (0.366, 4.903) 0.66 1.893 (0.765, 4.679) 0.17 2.018 (0.819, 4.976) 0.13
Previous VTE vs. no previous VTE 0.000(0.000, -) 1.0 0.000(0.000, -) 1.0 0.393 (0.123, 1.256) 0.12 0.348 (0.109, 1.109) 0.07
PE diagnosis after 48 h vs. within 48 h of admission 1.336 (0.362, 4.930) 0.41 0.636 (0.190, 2.127) 0.46 1.012 (0.465, 2.201) 0.98 1.011 (0.465, 2.196) 0.98
PESI per one point increment 1.480 (0.977, 2.242) 0.06 1.480 (0.985, 2.224) 0.06 1.325 (0.985, 1.784) 0.06 1.337 (0.996, 1.795) 0.053
Intermediate-high or high vs. low or intermediate low risk PE 2.800 (0.999, 7.849) 0.05 2.448 (0.872, 6.872) 0.09 0.627 (0.284, 1.387) 0.25 1.248 (0.595, 2.617) 0.56
Central vs. peripheral thrombus location 0.392 (0.128, 1.199) 0.10 0.653 (0.242, 1.762) 0.40 1.598 (0.748, 3.413) 0.23 1.391 (0.695, 2.783) 0.35

*In model 1, central PE was defined as saddle PE or PE with thrombus in the main pulmonary artery and peripheral PE as PE with more distal thrombus

**In model 2, central PE was defined as saddle PE or PE with thrombus in the main pulmonary artery or a lobar artery and peripheral PE as PE with more distal thrombus

BMI Body mass index, CI Confidence interval, CKD Chronic kidney disease, COPD Chronic obstructive pulmonary disease, PE Pulmonary embolism, PESI Pulmonary embolism severity index, VTE Venous thromboembolism