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. 2025 Mar 14;20:40. doi: 10.1186/s13014-025-02597-9

Table 2.

Feasibility of active heart sparing planning regarding coverage of the target and constraints in the OARs and heart parameters (t-test results)

Active heart sparing group
Structure Constraint Parameter Mean (SD)
Standard constraints
Lungs MLD ≤ 20 Gy MLD (Gy) 14,546 (3.896)
V20 Gy ≤ 35% V20 Gy (%) 25,871 (7.318)
V5 Gy < 65% V5 Gy (%) 58,500 (14.872)
Esophagus D mean 34 Gy D mean (Gy) 18,195 (7.486)
V55 Gy ≤ 33% V55 Gy (%) 11,803 (10.517)
V60 Gy ≤ 7% V60 Gy (%) 6,450 (8.526)
maximal dose < 105% of prescribed dose Vol > 105% prescribed dose (cc) 0,004 (0.020)
Heart sparing constraints
Heart MHD ≤ 10 Gy MHD (Gy) 6,208 (2.884)
V30 Gy < 20% V30 Gy (%) 4,305 (3.140)
Left ventricle D mean < 3 Gy D mean Gy 2,276 (1.756)
V5 Gy < 17% V5 Gy (%) 8,061 (17.065)
V23 Gy < 5% V23 Gy (%) 0,267 (1.262)
LAD D max < 17 Gy D max Gy 6,658 (3.324)
V15Gy < 10% V15 Gy (%) 0,090 (0.469)
V30 Gy < 2% V30 Gy (%) 0,000 (0.000)
Heart base D mean < 9 Gy D mean (Gy) 5,771 (2.003)
PTV Volume (cc) 293,041 (189.244)
D2% (Gy) 68,388 (1.485)
D98% (Gy) 56,642 (16.206)

PTV: planning target volume; SD, standard deviation, LAD: left anterior discending coronary artery; D mean: Mean dose; D max: maximal dose; MLD: mean lung dose; MHD: mean heart dose