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. Author manuscript; available in PMC: 2026 Mar 1.
Published in final edited form as: Resuscitation. 2025 Jan 23;208:110507. doi: 10.1016/j.resuscitation.2025.110507

Table 2: Multivariable logistic regression analyses.

DAG-guided
adjustment (a)		 ROSC

aOR [95% CI]		 Survival to
discharge

aOR [95% CI]		 Survival and discharge
home

aOR [95% CI]
Initial defibrillation dose
(per 1 J/kg, continuous)
Truncated exponential 		0.97 [0.92, 1.01]
n=7,240		 0.98 [0.87, 1.10]
n=1,245		 1.01 [0.89, 1.15]
n=1,245
Initial defibrillation dose
(per 1 J/kg, continuous)
Rectilinear 		1.00 [0.92, 1.09]
n=4,920		 0.89 [0.70, 1.12]
n=775		 0.77 [0.56, 1.02]
n=775
Initial defibrillation dose
(per 1 J/kg, continuous)
All defibrillation waveforms 		1.01 [0.98, 1.04]
n=21,121		 1.00 [0.92, 1.08]
n=2,981		 0.99 [0.91, 1.08]
n=2,981
Full multivariable
model (b)		 ROSC

aOR [95% CI]		 Survival to
discharge

aOR [95% CI]		 Survival and discharge
home

aOR [95% CI]
Initial defibrillation dose
(per 1 J/kg, continuous)
Truncated exponential 		0.98 [0.93, 1.03];
n=7,212		 0.96 [0.85, 1.10];
n=1,243		 1.00 [0.86, 1.16];
n=1,243
Initial defibrillation dose
(per 1 J/kg, continuous)
Rectilinear 		1.05 [0.96, 1.15];
n=4,893		 0.93 [0.71, 1.22];
n=775		 0.75 [0.54, 1.03];
n=775
Initial defibrillation dose
(per 1 J/kg, continuous)
All defibrillation waveforms * 		1.02 [0.99, 1.05]
n=20,993		 0.99 [0.92, 1.09
n=2,975		 0.99 [0.89, 1.09]
n=2,975
*

For entire model, see Supplemental Table 2.

DAG = directed acyclic graph, ROSC = return of spontaneous circulation (ROSC), aOR = adjusted odds ratio, J = Joules, kg = kilograms.