Table 2.

Multivariable analysis of mutant NPM1 MRD in patients with AML with a FLT3-ITD at diagnosis

Prognostic factor	Relapse incidence
	HR (95% CI)	P value
Mutant NPM1 MRD status (detectable vs not detectable)	4.79 (1.84-12.44)	.001
Age (per year)	1.00 (0.97-1.04)	.86
No. of cycles to attain CR (2 vs 1 cycle)	0.70 (0.26-1.85)	.47
WBC counts at diagnosis (>100 × 109 vs ≤100 × 109)	1.59 (0.78-3.22)	.20

WBC, white blood cell.