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. 2025 Feb 28;9:e58262. doi: 10.2196/58262

Table 2.

Outcome evaluation at baseline and 3 months for program participants versus those in the control group with endometriosis.

Health outcome Program participants (n=92), n (%) Control group (n=149), n (%) T0a T0+3 mo



Program participants, mean (SD) Control group, mean (SD) Participants vs control group Program participants, mean (SD) Control group, mean (SD) Participants vs control group





P value Cohen d

P value Cohen d
Global symptom burden 90 (97.8) 147 (98.7) 5.3 (1.6) 5.0 (1.6) .17 0.1b 4.6 (1.6) 4.7 (1.8) .75 –0.0b
Overall pain 90 (97.8) 147 (98.7) 6.2 (2.5) 6.0 (2.4) .68 0.1b 5.5 (2.6) 5.3 (2.6) .66 0.1b
Anxiety 90 (97.8) 147 (98.7) 6.5 (2.2) 5.9 (2.7) .12 0.2c 5.5 (2.9) 6.1 (2.7) .12 –0.2c
Depression 89 (96.7) 147 (98.7) 4.0 (3.0) 4.2 (3.2) .87 –0.0b 3.3 (3.1) 4.2 (3.3) .05 –0.3c
Dysmenorrhea 35 (38) 74 (49.7) 7.3 (1.8) 6.5 (2.3) .12 0.3c 5.6 (2.6) 5.8 (2.6) .54 –0.1b
Dyspareunia 43 (46.7) 84 (56.4) 3.9 (2.4) 4.1 (2.8) .90 –0.0b 3.1 (2.5) 3.5 (2.7) .47 –0.2c
Dyschezia 90 (97.8) 147 (98.7) 3.7 (3.2) 4.2 (2.8) .19 –0.2c 3.3 (2.7) 3.6 (2.9) .60 –0.1b
Dysuria 90 (97.8) 147 (98.7) 2.2 (2.9) 1.8 (2.5) .36 0.2c 1.6 (2.0) 1.6 (2.4) .35 0.0b
Chronic pelvic pain 90 (97.8) 147 (98.7) 5.2 (2.8) 4.8 (2.7) .22 0.2b 4.8 (2.8) 4.5 (2.7) .48 0.1b
Gastrointestinal disorders 90 (97.8) 147 (98.7) 5.9 (2.7) 5.3 (2.7) .10 0.2c 5.7 (2.3) 5.1 (2.8) .13 0.2c
Chronic fatigue 90 (97.8) 147 (98.7) 7.5 (2.1) 7.0 (2.2) .09 0.2c 6.8 (2.3) 6.8 (2.3) .77 –0.0b
Neuropathic pain 90 (97.8) 147 (98.7) 5.4 (3.1) 4.6 (3.2) .09 0.2c 4.3 (2.9) 4.5 (3.0) .47 –0.1b
Endo belly 90 (97.8) 147 (98.7) 6.2 (2.5) 5.7 (2.7) .09 0.2c 5.4 (2.7) 5.3 (2.7) .92 0.0b
QOLd: EHP-5e core part 39 (42.4) 65 (43.6) 53.8 (20.4) 45.2 (20.3) .04 0.0b 47.9 (19.4) 46.2 (21.5) .88 0.0b
QOL: EHP-5, modular part 39 (42.4) 64 (43) 34.9 (13.0) 28.7 (18.4) .05 0.4c 26.7 (15.4) 26.4 (18.8) .59 0.0b
QOL: EQ-5D score 33 (35.9) 80 (53.7) 0.8 (0.1) 0.8 (0.2) .06 –0.2c 0.9 (0.1) 0.8 (0.2) .44 0.0b

aT0: time point 0.

bNo effect size.

cSmall effect size.

dQOL: quality of life.

eEHP-5: Endometriosis Health Profile-5.