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. 2025 Feb 25;17(2):1459–1469. doi: 10.62347/WJGT6717

Figure 3.

Figure 3

PPP6C is directly targeted and down-regulated by miR-129-2-3p. A. The sequence of the predicted target site for miR-129-2-3p within the 3’UTR of PPP6C mRNA is highly conserved across different species. B. Pearson correlation was used to analyze the correlation between PPP6C mRNA expression and miR-129-2-3p expression in EC tissues. C. The predicted target binding sites of miR-129-2-3p in PPP6C 3’UTR. D. mRNA levels of PPP6C in EC cells after overexpression of miR-129-2-3p. E. Co-transfection of miR-129-2-3p mimic and PPP6C-WT significantly inhibited the luciferase activity of EC cells. *, P < 0.05; **, P < 0.01; and ***, P < 0.001.