Fig. 2.

Temporal gene expression dynamics profiling in gonad asymmetry. (A) The number of DEGs (FDR < 1 %) is shown for left and right gonads during development. Each horizontal comparison indicates the number of DEGs at each time point compared to embryonic day 5. (B) Venn diagrams show the DEGs between left and right gonads during development at each time point. (C) The k-means clustering of total differentially expressed genes is based on the expression dynamics and expression cluster shift of genes between left and right gonads. Respective gene expression is shown in gray, and the representative expression pattern is highlighted in different colors. A chord diagram indicates the number of DEGs that shifted clusters from left to right. (D) DEGs in the cell cycle pathway and their expression clusters between left and right gonads are shown on the left panel. The colors of the clusters correspond to the colors used in (C). A heatmap of gene expression for the pathway is on the right panel.