Table 2. Multifactor Cox regression analysis.

Variables	β	SE	Z	P	HR (95% CI)
Age
<60 years					1.00 (reference)
≥80 years	1.66	0.06	25.93	<0.001	5.23 (4.62–5.93)
60–69 years	0.42	0.07	6.09	<0.001	1.52 (1.33–1.73)
70–79 years	0.94	0.06	14.65	<0.001	2.56 (2.25–2.90)
Race
Black					1.00 (reference)
Others	−0.32	0.09	−3.33	<0.001	0.73 (0.61–0.88)
White	−0.24	0.07	−3.25	0.001	0.79 (0.68–0.91)
Marital
Married					1.00 (reference)
Others	0.29	0.03	8.44	<0.001	1.34 (1.25–1.43)
Single	0.29	0.05	5.70	<0.001	1.34 (1.21–1.48)
Primary site
Bladder neck					1.00 (reference)
Overlapping lesion of bladder	0.15	0.07	2.10	0.04	1.16 (1.01–1.34)
Ureteric orifice and urachus	−0.08	0.10	−0.88	0.38	0.92 (0.76–1.11)
Wall of bladder	−0.06	0.07	−0.95	0.34	0.94 (0.82–1.07)
Grade
Grade I					1.00 (reference)
Grade II	0.03	0.06	0.45	0.65	1.03 (0.91–1.16)
Grade III	0.44	0.07	6.67	<0.001	1.55 (1.36–1.76)
Grade IV	0.49	0.06	8.54	<0.001	1.63 (1.46–1.82)
Histology
Adenocarcinoma					1.00 (reference)
Others	−0.03	0.17	−0.15	0.88	0.97 (0.69–1.37)
Squamous cell carcinoma	0.07	0.18	0.37	0.71	1.07 (0.76–1.51)
Transitional cell carcinoma	−0.42	0.14	−3.06	0.002	0.66 (0.50–0.86)
Surgery
No					1.00 (reference)
Yes	−0.35	0.10	−3.62	<0.001	0.71 (0.59–0.85)
Radiation
No/unknown					1.00 (reference)
Yes	0.35	0.05	6.33	<0.001	1.41 (1.27–1.58)
Stage
Distant					1.00 (reference)
Localized	−1.85	0.06	−28.69	<0.001	0.16 (0.14–0.18)
Regional	−1.13	0.07	−16.50	<0.001	0.32 (0.28–0.37)
Prior cancer
No					1.00 (reference)
Yes	0.17	0.03	5.14	<0.001	1.19 (1.11–1.27)

CI, confidence interval; HR, hazards ratio; SE, standard error.