Table 2.

Pharmacokinetic (PK) parameters of CA after single oral administration AMX-CA 250 mg either formulation A or formulation B in dogs (Mean ± SD, n = 6)

PK Parameter	Unit	AMX-CA 250 mg formulations
		Formulation A	Formulation B
Cmax	µg/mL	1.22 ± 0.14	1.10 ± 0.15
Tmax	h	1.08 ± 0.19	1.33 ± 0.24
t1/2	h	1.55 ± 0.33	1.21 ± 0.35
kel	1/h	0.47 ± 0.10	0.61 ± 0.13
AUC0–4	µg∙h/mL	2.19 ± 0.30 a	1.72 ± 0.32
AUC0-∞	µg∙h/mL	2.80 ± 0.52 a	2.06 ± 0.51

C_max peak plasma concentration, T_max time to achieve peak concentration, t_1/2 elimination half-life, k_el elimination rate constant, AUC_0-4 area under the plasma concentration versus time curve from 0 to 4 h (the last measurable timepoint), AUC_0-∞ area under the plasma concentration versus time curve extrapolated to infinity

^asignificant difference between columns (p < 0.05)