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. 2024 Jul 5;101(2):338–349. doi: 10.1111/php.13998

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© 2024 The Author(s). Photochemistry and Photobiology published by Wiley Periodicals LLC on behalf of American Society for Photobiology.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Microscopic appearance of UVR‐exposed skin. Skin sections were prepared from mice subjected to the 5‐week treatment cycle of UVR‐only, or UVR + NEO400 (Schedule A). Histological characteristics were examined under the microscope. As exemplified in these images, the epidermis of UVR‐only skin showed signs of: (1) hypergranulosis, (2) dyskeratosis, (3) hyperplasic epidermis, and (4) abnormal structures with ductal differentiation, which were not apparent in skin sections from mice that had received NEO400 immediately following UVR exposure.