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. 2025 Mar 17;37(1):94. doi: 10.1007/s40520-025-03007-6

Table 2.

Pearson’s correlations of Cystatin-C/total cholesterol ratio at wave 6 with the development of low HGS in waves 7, 8, and 9 in the study population (n = 17,698). (HGS; handgrip strength, BMI; body mass index)

Characteristic Level Correlation Coefficient 95% CI P Value
Lower Upper
Gender Male 0.169 0.148 0.191 < 0.001
Female 0.143 0.124 0.162 < 0.001
Age 50–60 -0.016 -0.047 0.015 0.000
60–69 0.081 0.057 0.104 < 0.001
70–79 0.092 0.064 0.120 < 0.001
80–89 0.048 -0.003 0.098 0.000
90+ 0.125 -0.097 0.336 0.000
BMI Underweight 0.232 0.038 0.409 0.000
Normal 0.182 0.158 0.206 < 0.001
Overweight 0.147 0.125 0.170 < 0.001
Obese 0.118 0.087 0.149 < 0.001
Missing 0.129 0.004 0.250 0.000
Quality of life Low 0.158 0.046 0.266 0.000
Medium 0.130 0.103 0.156 < 0.001
High 0.147 0.130 0.165 < 0.001
Missing 0.222 0.120 0.320 < 0.001
Euro depression scale No depression 0.143 0.112 0.173 < 0.001
Low 0.148 0.128 0.167 < 0.001
Medium 0.162 0.129 0.195 < 0.001
High 0.114 0.040 0.187 < 0.001
Missing 0.404 0.220 0.560 < 0.001
Diff. with climbing several flights of stairs No 0.127 0.111 0.143 < 0.001
Yes 0.132 0.100 0.164 < 0.001
Difficulty getting up from chair No 0.141 0.125 0.157 < 0.001
Yes 0.165 0.130 0.200 < 0.001
Difficulty getting dressed No 0.146 0.132 0.161 < 0.001
Yes 0.170 0.107 0.231 < 0.001
Bothered by frailty, falling down No 0.153 0.138 0.168 < 0.001
Yes 0.112 0.048 0.176 < 0.001
High blood pressure No 0.162 0.143 0.181 < 0.001
Yes 0.119 0.096 0.142 < 0.001
Diabetes or high blood sugar No 0.152 0.137 0.167 < 0.001
Yes 0.109 0.068 0.150 < 0.001
Cancer No 0.155 0.140 0.170 < 0.001
Yes 0.124 0.047 0.200 0.000
Alzheimer’s disease No 0.157 0.142 0.171 < 0.001
Yes -0.191 -0.367 -0.002 0.000
Stroke No 0.157 0.142 0.171 < 0.001
Yes 0.029 -0.063 0.120 0.000
Osteoarthritis No 0.152 0.136 0.168 < 0.001
Yes 0.157 0.124 0.190 < 0.001