TABLE 2.

Direct healthcare resource consumptions and costs, in euro price year 2023 from the health system perspective.

	All patients (n = 92)	Type 1 (n = 43)	Type 2 (n = 16)	Type 3 (n = 20)	Type 4 (n = 13)
Overall patient trajectory, Mean cost (€) [95% CI]	21,324.05 [14,661.89; 31,314.91]	5,820.12 [3,823.34; 9,448.58]	22,285.32 [11,254.33; 50,850.47]	27,541.11 [13,654.4; 55,149.85]	61,858.45 [32,130.42; 103,396.4]
All hospitalizations, mean [95% CI]	2.71 [1.99; 4.76]	1 [0.74; 1.35]	4.12 [2.62; 6.69]	5 [2.35; 14.25]	3.08 [1.69; 5.85]
Mean cost (€)  [95% CI]	21,004.68 [14,392.35; 31,242.44]	5,572.9 [3,537.69; 9,209.7]	21,683.02 [10,588.7; 50,689.53]	27,285.41 [13,228.77; 53,641.06]	61,550.7 [32,392.09; 103,561]
Hospitalizations for heart failure, mean [95% CI]	0.75 [0.54; 1]	0.49 [0.3; 0.77]	0.62 [0.19; 1.6]	1.1 [0.55; 1.75]	1.23 [0.69; 1.77]
Mean cost (€)  [95% CI]	10,812.55 [5,985.37; 18,915.73]	2,325.9 [1,260.87; 5,412.92]	3,171.05 [1,134.39; 9,308.26]	18,728.11 [5,558.03; 46,912.62]	36,110.92 [13,651.36; 74,642.67]
Hospital medical consultations, mean [95% CI]	3.46 [2.58; 4.54]	2.4 [1.44; 3.77]	6.75 [4.25; 9.44]	2.7 [1.25; 5.1]	4.08 [1.92; 8.92]
Mean cost (€)  [95% CI]	190.11 [142.88; 250.49]	131.74 [79.3; 211.05]	371.25 [233.75; 522.5]	148.5 [66; 269.09]	224.23 [105.77; 477.12]
Hospital medical procedures, mean [95% CI]	1.36 [0.96; 1.84]	1.21 [0.7; 2.05]	2.38 [1.38; 3.69]	1.15 [0.5; 2.25]	0.92 [0.23; 2]
Mean cost (€)  [95% CI]	129.26 [92.94; 176.3]	115.48 [65.31; 190.79]	231.05 [133.93; 374.01]	107.2 [49.31; 213.34]	83.52 [22.27; 181.88]

CI, confidence interval.

All costs were expressed in euros (€) at 2023 price year and adjusted for inflation based on the French National Institute of Statistics and Economic Studies (INSEE) Consumer Price Indices of the healthcare products and services.

Cost differences between groups were considered statistically significant if the bootstrapped 95% CIs did not overlap.