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. Author manuscript; available in PMC: 2025 Apr 1.
Published in final edited form as: Am J Psychiatry. 2024 Feb 29;181(4):322–329. doi: 10.1176/appi.ajp.20230376

TABLE 2.

Characteristics of parents and offspring in a study of risk of psychopathology among the children of parents with alcohol use disorder

Measure All Offspring (N=l,244,516) Female Offspring (N=598,701) Male Offspring (N=645,815) Biological Mother (1,244,516) Biological Father (1,244,516)
Mean SD Mean SD Mean SD Mean SD Mean SD
Year of birth 1979.9 6.1 1979.9 6.1 1979.8 6.1 1951.7 7.1 1949.0 7.5
Age at follow-up (years) 37.7 6.8 37.5 6.9 37.8 6.8 66.2 7.2 68.3 7.3
N % N % N % N % N %
Prevalence
 Alcohol use disorder 33,863 2.72 9,520 1.59 24,343 3.77 26,404 2.12 76,536 6.15
 Drug use disorder 43,629 3.51 12,089 2.02 31,540 4.88 13,622 1.09 12,621 1.01
 ADHD 26,039 2.09 11,544 1.93 14,495 2.24 2,789 0.22 2,772 0.22
 Major depression 189,529 15.23 119,755 20.00 69,774 10.80 200,097 16.08 118,250 9.50
 Anxiety disorder 185,436 14.90 115,581 19.31 69,855 10.82 144,003 11.57 77,696 6.24
Mean SD Mean SD Mean SD Mean SD Mean SD
Age at first diagnosis (years)
 Alcohol use disorder 28.3 8.2 28.7 8.6 28.1 8.1 55.2 10.6 52.3 14.6
 Drug use disorder 26.2 6.8 27.3 7.7 25.7 6.4 54.3 10.9 55.3 12.5
 ADHD 30.0 7.9 30.7 7.4 29.5 8.2 55.9 7.5 57.4 7.9
 Major depression 31.0 7.0 30.7 7.0 31.4 7.0 56.0 10.4 59.3 10.9
 Anxiety disorder 31.2 6.9 31.0 7.0 31.4 6.8 57.9 10.0 60.3 10.4