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. 2025 Feb 20;26:102298. doi: 10.1016/j.fochx.2025.102298

Table 4.

. Regulations for the use of silver nanoparticles/nanomaterials in the food and agriculture industry.

Country/Region Regulatory Body Food Industry Regulations Agriculture Regulations Key Applications Notes Reference
United States FDA, EPA It requires safety assessments for food contact materials; nanosilver is allowed in antimicrobial packaging. Regulated under pesticide laws; nanosilver-based fertilizers require EPA approval. Food packaging, pest control Emphasis on environmental safety and human health. (Kumari et al., 2023)
European Union EFSA, ECHA Strict limits on nanoparticle size (<10 nm) and concentrations; mandates product labeling. Controlled under EU pesticide laws; approval is needed for specific uses. Pesticides, biodegradable coatings Focus on consumer safety and reducing environmental impact. (Nielsen et al., 2023; Singh et al., 2024)
Japan Ministry of Health, Labour and Welfare Requires safety evaluations for novel food additives containing nanoparticles. Strict pre-approval for agricultural chemicals with nanosilver. Advanced nanotechnology research Strong emphasis on innovation and public safety. Peters et al., 2016)
China CFSA, Ministry of Agriculture Mandates detailed safety evaluations; growing interest in regulating nanosilver applications. Regulated under agricultural safety laws; environmental impact assessments are needed. Food storage, fertilizers Rapidly evolving regulations to meet international standards. (“China Notifies for Safety Evaluation Materials for “Three New Foods” [WWW Document, 2024)
Australia FSANZ, APVMA Requires pre-market approval for food products with nanomaterials. Nanosilver fertilizers are regulated as agricultural chemicals; safety data is required. Veterinary products, food coatings Strong focus on consumer and environmental protection. (“Australian Pesticides and Veterinary Medicines Authority, 2010)