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. 2025 Mar 5;16:1513060. doi: 10.3389/fimmu.2025.1513060

Table 1.

Demographic, laboratorial and clinical features of the study population.

Groups (n) Sex AgeMedian (Min-Max) Bacilloscopic IndexMedian (Min-Max) Number of LesionsMedian (Min-Max) Affected Nerves Median (Min-Max)
Malen (%) Femalen (%)
NI 18 8 (44.4) 10 (55.6) 39 (23-56) - - -
HHC 7 2 (28.6) 5 (71.4) 38 (21-54)
L(PB) 14 6 (42.9) 8 (57.1) 39 (31-47) 0 (0-0) 1.0 (1-5) 0 (0-3)
L(MB) 13 7 (53.8) 6 (46.2) 48 (34-58) 4.0 (2.5-5.5)* 20 (7-20)* 1.0 (0-3)
T1LR 12 9 (75.0) 3 (25) 49 (21-62) 0 (0-3.5) 20 (1-30) 2 (0-3)
T2LR 11 10 (90.9) 1 (9.1) 45 (27-64) 3.0 (2.8-5.0)** 20 (20-30) 2 (0-2)

NI = Non-Infected healthy volunteers with no clinical history of leprosy; HHC = households contacts of Leprosy patients; L(PB) = Paucibacillary Leprosy; MB – Multibacillary Leprosy patients; T1LR – patients with Type 1 Leprosy Reaction; T2LR – patients with Type 2 Leprosy Reaction. No significant difference was observed for age distribution by Kruskal-Wallis (p= 0.0714). No significant difference was observed for sex distribution by Chi-square Test (p=0.0633). *Higher bacilloscopic index and number of lesions were observed in L(MB) as compared with L(PB) by Mann-Whitney test (p= 0,0002; p= 0,0008, respectively); **Higher bacilloscopic index was observed in T2LR as compared to T1LR by Mann-Whitney test (p= 0,0242).