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Representative images. (A–C) Adenocarcinoma of the colonic hepatic flexure (case number 14) with mucinous differentiation (A, ×100) showing diffuse SLFN11 staining (B, ×100) and MSH6 loss (C, ×100) by immunohistochemistry; this tumor had mutations in MSH6 and KRAS genes. (D–F) BRAF V600E‐mutated carcinoma of the cecum (case number 4) (D, ×100) with SLFN11 positivity (E, ×100) and MLH1 loss (F, ×100).
