Table 2.
Associations between the SIRI and age-related macular degeneration risk in the total cohort.
| SIRI | Cases with AMD/N | Model 1a | Model 2b | Model 3c | |||
|---|---|---|---|---|---|---|---|
| OR (95%CI) | p value | OR (95%CI) | p value | OR (95%CI) | p value | ||
| Tertile categories | |||||||
| Tertile 1 (0.060–0.826) | 105/1790 | 1 | 1 | 1 | |||
| Tertile 2 (0.827–1.318) | 125/1787 | 1.21 (0.92–1.58) | 0.169 | 1 (0.76–1.32) | 0.977 | 0.98 (0.75–1.3) | 0.912 |
| Tertile 3 (1.319–20.500) | 195/1788 | 1.96 (1.53–2.51) | <0.001 | 1.44 (1.11–1.87) | 0.006 | 1.36 (1.05–1.77) | 0.021 |
| P for trend | <0.001 | 0.001 | 0.006 | ||||
| Continuous values (0.060–20.500) | 425/5365 | 1.34 (1.22–1.47) | <0.001 | 1.21 (1.1–1.33) | <0.001 | 1.18 (1.07–1.29) | 0.001 |
a
Model 1 was crude model and adjusted for nothing.
b
Model 2 was adjusted for age, gender, marital status, race.
c
Model 3 included the covariates of Model 2 with additional adjustment for obesity, hypertension, diabetes, smoking status.
SIRI, systemic inflammatory response index; OR, odds ratio; CI, confidence interval.