Table 2. GlyT1 Binding Data for SSR504734 in the Rat Brain Cortex.
| concentration [μM] | % inhibition of control specific bindinga |
|---|---|
| 0.1 | 42 |
| 20 | 52 |
| 100 | 62 |
Results showing activity higher than 50% are considered to represent significant effects of the test compounds; results showing an inhibition between 25 and 50% are indicative of a moderate effect.