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. 2025 Feb 27;16(6):1210–1226. doi: 10.1021/acschemneuro.5c00039

Table 2. GlyT1 Binding Data for SSR504734 in the Rat Brain Cortex.

concentration [μM] % inhibition of control specific bindinga
0.1 42
20 52
100 62
a

Results showing activity higher than 50% are considered to represent significant effects of the test compounds; results showing an inhibition between 25 and 50% are indicative of a moderate effect.