Figure 4.
Sensor detection of uPA in human blood products. (A) Comparison of the change in center wavelength after addition of 100 nM uPA in bovine serum, human serum, and EDTA human plasma. Bars represent the mean ± of three experiments. Sensor wavelength difference between experiments and statistical analysis: bovine serum and human serum (0.44 nm; p = 0.48); bovine serum and human plasma (0.23 nm; p = 0.86); human serum and human plasma (0.21 nm; p = 0.88); two-sided one-way ANOVA with Tukey posthoc analysis, p > 0.05 was considered Not Significant (NS). (B) Change in sensor fluorescence emission center wavelength as a result of addition of 100 nM uPA over time compared to sensor without uPA added in 10% human EDTA plasma and 10% human serum. Points represent the mean ± SD of three experiments.