Table 1.
Baseline Characteristics
| Demographics | TRE (n=61) | SOC (n=61) |
|---|---|---|
| Age, years* | 56.6 (11.5) | 60.6 (10.3) |
| Male, n (%) | 30 (49 | 30 (49) |
| Female, n (%) | 31 (51) | 31 (51) |
| White, n (Hispanic or Latino, n) | 36 (1) | 38 (2) |
| Black, n (Hispanic or Latino, n) | 7 (0) | 2 (0) |
| Asian, n (Hispanic or Latino, n) | 10 (0) | 16 (0) |
| Native Hawaiian or Other Pacific Islander, n (Hispanic or Latino, n) |
2 (0) | 0 |
| Mixed Race, n (Hispanic or Latino) | 4 (2) | 5 (3) |
| Declined to disclose race/ethnicity, n | 2 | 0 |
| Medications for Treatment of Metabolic Syndrome | ||
| Metformin, n (%) | 4 (7) | 3 (5) |
| Statins, n (%) | 29 (48) | 31 (52) |
| Anti-Hypertensives and Diuretics, n (%) | 28 (46) | 31 (52) |
| Non-statin lipid-lowering drugs, n (%) | 2 (3) | 2 (3) |
| 1 or more medication listed above, n (%) | 46 (75) | 38 (62) |
| Metabolic Syndrome Classification | ||
| HbA1c ≥ 5.7 %, Fasting Glucose ≥ 5.55 mmol/L (100 mg/dL) or drug treatment, n (%) | 61 (100) | 61 (100) |
| HDL cholesterol: M < 1.03 mmol/L (40 mg/dL) or F < 1.29 mmol/L (50 mg/dL) (F), or drug treatment for reduced HDL-cholesterol, n (%) | 44 (73) | 42 (69) |
| Triglycerides ≥ 1.69 mmol/L (150 mg/dL) or drug treatment for elevated triglycerides, n (%) | 25 (41) | 25 (41) |
| SBP ≥ 130 mmHg and/or DBP ≥ 85 mmHg, or Drug Treatment for Hypertension, n (%) | 48 (79) | 44 (73) |
| Waist Circumference: Asian: ≥ 90 cm (M) or ≥ 80 cm (F); all other races: ≥ 102 cm (M) or ≥ 88 cm (F), n (%) | 52 (85) | 55 (90) |
Baseline characteristics for all randomized participants (n=122). All data are presented as mean (SD) unless otherwise specified. Independent T-tests were used to assess differences between groups, with p-value <0.05 considered significant (*). Only age was significantly different between TRE and SOC at baseline (p=0.044). Non-statin lipid-lowering drugs include fenofibrate, icosapent ethyl, ezetimibe, and omega-3 fatty acid ethyl ester. TRE = time-restricted feeding, SOC = standard of care, HbA1c = hemoglobin A1c (glycated hemoglobin), SBP = systolic blood pressure, DBP = diastolic blood pressure.