Skip to main content
. Author manuscript; available in PMC: 2026 Apr 1.
Published in final edited form as: Hear Res. 2025 Jan 22;459:109201. doi: 10.1016/j.heares.2025.109201

Figure 11.

Figure 11.

The structural integrity of pillar cells in regions with complete OHC loss. (A) Actin staining of the reticular lamina in a cyclodextrin-treated cochlea. All OHCs are absent, as indicated by the loss of actin staining in the cuticular plates of OHCs. (B) A side view of the region of the organ of Corti marked by the orange rectangle in panel A. The image was generated by digital sectioning of confocal images of the region. Note that the pillar cells maintain their vertical orientation (arrow), supporting the arch of the tunnel of Corti. (C) Actin staining of the reticular lamina in a cyclodextrin-treated cochlea. The image shows the boundary area between the region where pillar cells are visible and the region where they are no longer visible. The orange rectangle marks pillar cells next to the area of missing pillar cells. (D) The side view of the organ of Corti marked by the orange rectangle in panel C. Note that the surviving pillar cells near the areas of missing pillar cells sag (arrow), indicating compromised structural support.