Table 4.
Multivariable Analysis for Sources of Clostridium difficile Acquisition in Patients Having Community-Associated C difficile Infection With No or Low-Level Outpatient Health Care Exposure, 2009 Through 2011a
| Odds Ratio (95% CI) |
||
|---|---|---|
| Variable | No Exposure | Low-Level Exposure |
|
| ||
| No medical conditions | 1.1 (0.8–1.6) | 1.7 (1.3–2.3) |
| Household members | ||
| Infant younger than 1 y | 1.8 (0.7–4.6) | 2.1 (1.1–4.5) |
| With active C difficile infection | 6.8 (0.7–65.9) | 6.9 (0.9–56.7) |
Odds ratios were calculated using multinomial logistic regression using high-level outpatient health care exposure as the reference group. Candidate variables included clinical characteristics (age, sex, and no medical conditions), potential sources of C difficile infection (infant younger than 1 year, household member with active C difficile infection, and children younger than 4 years who attended child care settings), and antibiotic use as an interaction term with potential sources of C difficile infection. The final model was selected using a backward logistic regression strategy with a stay criterion of P ≤ .10 for variables.