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Calculated bevacizumab vitreous half-lives in days.
| Injection location | Case 1a | Case 1b | Case 2a | Case 2b |
|---|---|---|---|---|
| Rabbit | ||||
| Anterior vitreous | 2.12 | 0.38 | 3.26 | 0.38 |
| Middle vitreous (slow convection) | 2.12 | 0.38 | 3.27 | 0.38 |
| Middle vitreous (fast convection) | 1.00 | 0.32 | 3.27 | 0.38 |
| Posterior vitreous | 2.14 | 0.38 | 3.27 | 0.38 |
| Human | ||||
| Anterior vitreous | 5.29 | 1.20 | 10.00 | 1.27 |
| Middle vitreous (slow convection) | 5.36 | 1.19 | 10.25 | 1.27 |
| Middle vitreous (fast convection) | 1.62 | 0.68 | 10.25 | 1.27 |
| Posterior vitreous | 5.46 | 1.19 | 10.56 | 1.27 |
