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Calculated bevacizumab duration of action in the vitreous in days.
| Injection location | Case 1a | Case 1b | Case 2a | Case 2b |
|---|---|---|---|---|
| Rabbit | ||||
| Anterior vitreous | 17.0 | 3.0 | 26.0 | 3.0 |
| Middle vitreous (slow convection) | 18.0 | 3.0 | 27.5 | 3.0 |
| Middle vitreous (fast convection) | 8.5 | 2.5 | 27.5 | 3.0 |
| Posterior vitreous | 18.0 | 3.0 | 28.0 | 3.0 |
| Human | ||||
| Anterior vitreous | 34.0 | 8.0 | 61.5 | 8.5 |
| Middle vitreous (slow convection) | 36.0 | 8.5 | 67.5 | 9.0 |
| Middle vitreous (fast convection) | 11.5 | 5.0 | 67.5 | 9.0 |
| Posterior vitreous | 37.0 | 8.0 | 70.5 | 8.5 |
